Mouse Anti-CGB3 Recombinant Antibody (CBT4506) (V2LY-0625-LY510)

Name: Mouse Anti-CGB3 Recombinant Antibody (CBT4506)
SKU: V2LY-0625-LY510
Rating: 5 (1 reviews)

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Tested Data

Mouse Anti-CGB3 Recombinant Antibody (CBT4506) (V2LY-0625-LY510) in ELISA

Mouse Anti-CGB3 Recombinant Antibody (CBT4506) (V2LY-0625-LY510) in WB

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBT4506

Antibody Isotype

IgG1

Application

Basic Information

Immunogen

Purified recombinant fragment of human CGB (AA: 21-165) expressed in E. Coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500-1:2,000
ELISA	1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Chorionic Gonadotropin, beta polypeptide Peptide 1

Entrez Gene ID

1082

UniProt ID

P01233

Function

Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Biological Process

Apoptotic process Source: ProtInc
Cell-cell signaling Source: ProtInc
Female gamete generation Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Hormone-mediated signaling pathway Source: GO_Central
Peptide hormone processing Source: Reactome
Regulation of transcription by RNA polymerase II Source: Reactome
Signal transduction Source: ProtInc

Cellular Location

Secreted

More Infomation

References

Singh, P., Chalertpet, K., Sukbhattee, J., Wongmanee, N., Suwannakart, P., & Yanatatsaneejit, P. (2022). Association between promoter methylation and gene expression of CGB3 and NOP56 in HPV‑infected cervical cancer cells. Biomedical Reports, 16(1), 1-12.

Biskup, K., Blanchard, V., Castillo-Binder, P., Alexander, H., Engeland, K., & Schug, S. (2020). N-and O-glycosylation patterns and functional testing of CGB7 versus CGB3/5/8 variants of the human chorionic gonadotropin (hCG) beta subunit. Glycoconjugate journal, 37(5), 599-610.

Śliwa, A., Kubiczak, M., Szczerba, A., Walkowiak, G., Nowak-Markwitz, E., Burczyńska, B., ... & Jankowska, A. (2019). Regulation of human chorionic gonadotropin beta subunit expression in ovarian cancer. BMC cancer, 19(1), 1-9.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote
Second antibody and isotype control

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