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Rabbit Anti-CLEC4G Recombinant Antibody (CBWJC-2786) (CBMAB-C3900WJ)

This product is a Rabbit antibody that recognizes CLEC4G. This antibody CBWJC-2786 can be used for immunoassay techniques such as: WB, IHC-P.
See all CLEC4G antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Human
Clone
CBWJC-2786
Antibody Isotype
IgG
Application
WB, IHC-P

Basic Information

Specificity
Mouse, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
0.077 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
C-Type Lectin Domain Family 4 Member G
Introduction
This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the T-cell immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Entrez Gene ID
Human339390
Mouse75863
UniProt ID
HumanQ6UXB4
MouseQ8BNX1
Alternative Names
C-Type Lectin Domain Family 4 Member G; Liver And Lymph Node Sinusoidal Endothelial Cell C-Type Lectin; C-Type Lectin Superfamily 4, Member G; LSECtin; C-Type Lectin Domain Family 4, Member G; DTTR431; LP2698; UNQ431;
Function
Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca2+-dependent manner, in vitro.

(Microbial infection) Acts as a receptor for Japanese encephalitis virus.

(Microbial infection) Acts as a receptor for Ebolavirus.

(Microbial infection) Acts as a receptor for SARS-CoV.

(Microbial infection) Acts as a receptor for Lassa virus and Lymphocytic choriomeningitis virus glycoprotein (PubMed:22156524, PubMed:22673088).
Biological Process
Negative regulation of T cell mediated immunity Source: Ensembl
Negative regulation of T cell proliferation Source: Ensembl
Positive regulation of viral life cycle Source: FlyBase
Regulation of immune response Source: Reactome
Viral entry into host cell Source: FlyBase
Cellular Location
Cell membrane
Topology
Cytoplasmic: 1-31
Helical: 32-52
Extracellular: 53-293
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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