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Mouse Anti-CLEC4G Recombinant Antibody (CF104) (CBMAB-FT380LY)

The product is antibody recognizes CLEC4G . The antibody CF104 immunoassay techniques such as: ELISA, WB.
See all CLEC4G antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CF104
Antibody Isotype
IgG2a
Application
ELISA, WB

Basic Information

Immunogen
C-type lectin domain family 4, member G
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
C-Type Lectin Domain Family 4 Member G
Introduction
This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the T-cell immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Entrez Gene ID
339390
UniProt ID
Q6UXB4
Function
Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca2+-dependent manner, in vitro.

(Microbial infection) Acts as a receptor for Japanese encephalitis virus.

(Microbial infection) Acts as a receptor for Ebolavirus.

(Microbial infection) Acts as a receptor for SARS-CoV.

(Microbial infection) Acts as a receptor for Lassa virus and Lymphocytic choriomeningitis virus glycoprotein (PubMed:22156524, PubMed:22673088).
Biological Process
Negative regulation of T cell mediated immunity Source: Ensembl
Negative regulation of T cell proliferation Source: Ensembl
Positive regulation of viral life cycle Source: FlyBase
Regulation of immune response Source: Reactome
Viral entry into host cell Source: FlyBase
Cellular Location
Cell membrane
Topology
Cytoplasmic: 1-31
Helical: 32-52
Extracellular: 53-293
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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