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Mouse Anti-CLINT1 (AA 161-261) Recombinant Antibody (CBFYE-0339) (CBMAB-E0632-FY)

This product is mouse antibody that recognizes CLINT1. The antibody CBFYE-0339 can be used for immunoassay techniques such as: ELISA, IHC, WB.
See all CLINT1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBFYE-0339
Antibody Isotype
IgG1, κ
Application
ELISA, IHC, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa161-261 from ENTH with GST tag. MW of the GST tag alone is 26kD.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 161-261

Target

Full Name
Clathrin Interactor 1
Introduction
This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants.
Entrez Gene ID
Human9685
Mouse216705
Rat360515
UniProt ID
HumanQ14677
MouseQ99KN9
RatQ6DGF2
Alternative Names
Clathrin Interactor 1; Epsin-Related Protein; Enthoprotin; EpsinR; CLINT; ENTH; EPN4
Function
Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.
Biological Process
Clathrin coat assembly Source: Ensembl
Endocytosis Source: GO_Central
Post-Golgi vesicle-mediated transport Source: Reactome
Cellular Location
Cytoplasm; Perinuclear region; Clathrin-coated vesicle. Found throughout the cell, with the exception of the cell surface. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the trans-Golgi network.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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