CLINT1

This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
Full Name
Clathrin Interactor 1
Function
Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.
Biological Process
Clathrin coat assembly Source: Ensembl
Endocytosis Source: GO_Central
Post-Golgi vesicle-mediated transport Source: Reactome
Cellular Location
Cytoplasm; Perinuclear region; Clathrin-coated vesicle. Found throughout the cell, with the exception of the cell surface. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the trans-Golgi network.
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Anti-CLINT1 antibodies

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Mouse Anti-CLINT1 Recombinant Antibody (8B6) (CBMAB-C9060-LY)

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Target: CLINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 8B6
Application*: WB
Datasheet SDS

Mouse Anti-CLINT1 Recombinant Antibody (1E6) (CBMAB-C3963-LY)

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Target: CLINT1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E6
Application*: E, P, WB, IF
Datasheet SDS

Mouse Anti-CLINT1 Recombinant Antibody (CBFYC-1946) (V2LY-1206-LY237)

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Target: CLINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBFYC-1946
Application*: WB
Datasheet SDS

Mouse Anti-CLINT1 Recombinant Antibody (6G10) (V2LY-1206-LY235)

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Target: CLINT1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: 6G10
Application*: WB
Datasheet SDS

Mouse Anti-CLINT1 Recombinant Antibody (10F12) (V2LY-1206-LY233)

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Target: CLINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 10F12
Application*: WB
Datasheet SDS

Mouse Anti-CLINT1 Recombinant Antibody (CBFYE-0339) (V2LY-1206-LY232)

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Target: CLINT1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYE-0339
Application*: WB, IP, IF, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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