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  |  

Mouse Anti-FAS2 Recombinant Antibody (1D4) (CBMAB-0071-CN)

This product is a mouse antibody that recognizes FAS2 of Drosophila. The antibody 1D4 can be used for immunoassay techniques such as: ELISA, IF, IHC, WB.
See all FAS2 antibodies

Summary

Host Animal
Mouse
Specificity
Common fruit fly
Clone
1D4
Antibody Isotype
IgG1
Application
ELISA, IF, IHC, WB

Basic Information

Specificity
Common fruit fly
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Fas2
Introduction
In Drosophila, Fasciclin 2 (Fas2) has been intensively studied due to its role in nervous system development and maintenance; yet, Fas2 is most abundantly expressed in the adult renal (Malpighian) tubule rather than in neuronal tissues. Fas2 is essential to brush border maintenance in renal tubules of Drosophila. Fas2 is dynamically expressed during tubule morphogenesis, localizing to the brush border whenever the tissue is transport competent. The protein acts as a neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles.
Entrez Gene ID
31364
UniProt ID
P34082
Alternative Names
1D4; Ab 1D4; anon-EST:Liang-1.60; CG3665; clone 1.60; CT12301; Dmel\CG3665; EG:EG0007.3; Fas; FAS 11; Fas 2; fas II; Fas II; FAS II; fas-II; Fas-II; fas2; FAS2; fasciclin II; FascII; fasII; Fasii; FasII; FASII; l(1)G0032; l(1)G0048; l(1)G0081; l(1)G0293; l(1)G0336; mAb 1D4; mAb1D4; mAB1D4; MAB1D4
Research Area
Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles.
Biological Process
Axonal fasciculation Source: FlyBase
Axon guidance Source: GO_Central
Behavioral response to ethanol Source: FlyBase
Bolwig's organ morphogenesis Source: FlyBase
Cell morphogenesis involved in neuron differentiation Source: FlyBase
Dendrite self-avoidance Source: GO_Central
Homophilic cell adhesion via plasma membrane adhesion molecules Source: FlyBase
Imaginal disc-derived male genitalia morphogenesis Source: FlyBase
Learning or memory Source: FlyBase
Motor neuron axon guidance Source: FlyBase
Mushroom body development Source: FlyBase
Negative regulation of epidermal growth factor receptor signaling pathway Source: FlyBase
Negative regulation of neuron remodeling Source: FlyBase
Neuromuscular junction development Source: FlyBase
Neuron recognition Source: FlyBase
Olfactory learning Source: FlyBase
Photoreceptor cell axon guidance Source: FlyBase
Regulation of synapse structure or activity Source: FlyBase
Regulation of synaptic assembly at neuromuscular junction Source: FlyBase
Regulation of synaptic plasticity Source: FlyBase
Regulation of tube diameter, open tracheal system Source: FlyBase
Regulation of tube length, open tracheal system Source: FlyBase
Short-term memory Source: FlyBase
Synapse organization Source: FlyBase
Terminal button organization Source: FlyBase
Cellular Location
Cell membrane
Topology
Extracellular: 29-751
Helical: 752-769
Cytoplasmic: 770-873
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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