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Mouse Anti-CCT6A/B Recombinant Antibody (CBXC-0168) (CBMAB-C5570-CQ)


See all CCT6A/B antibodies
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Published Data
CBMAB-C5570-CQ-1
Mouse Anti-CCT6A/B Recombinant Antibody (CBXC-0168) (CBMAB-C5570-CQ) in WB
THOC3 expression in cells transfected with si-NC or si-CCT8/CCT6 shown by WB. ...View More
Yu, T., Zhang, Q., Yu, S. K., Nie, F. Q., Zhang, M. L., Wang, Q., & Lu, K. H. (2023). THOC3 interacts with YBX1 to promote lung squamous cell carcinoma progression through PFKFB4 mRNA modification. Cell Death & Disease, 14(7), 475. Distributed under Open Access license CC BY 4.0, without modification.
CBMAB-C5570-CQ-2
Mouse Anti-CCT6A/B Recombinant Antibody (CBXC-0168) (CBMAB-C5570-CQ) in IF
CCT/TRiC complex subunits beta and zeta (CCT2 and CCT6A) and proteasome subunit alpha 3 (PSMA3) interact with claudin-3 in MDCK-C7 cells. ...View More
Suarez-Artiles, L., Breiderhoff, T., Girardello, R., Gonschior, H., Rodius, S., Lesur, A., ... & Dittmar, G. (2022). Pan-claudin family interactome analysis reveals shared and specific interactions. Cell Reports, 41(6). Distributed under Open Access license CC BY 4.0, without modification.

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBXC-0168
Antibody Isotype
IgG1, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 342-531 mapping at the C-terminus of TCP-1 ζ of human origin.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Chaperonin Containing TCP1 Subunit 6B
Introduction
CCT6B (Chaperonin Containing TCP1 Subunit 6B) is a Protein Coding gene. Diseases associated with CCT6B include Pelvic Varices. Among its related pathways are Chaperonin-mediated protein folding and Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding. Gene Ontology (GO) annotations related to this gene include unfolded protein binding and protein transporter activity. An important paralog of this gene is CCT6A.
Entrez Gene ID
10693
UniProt ID
Q92526
Function
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.
Biological Process
Protein folding Source: FlyBase
Toxin transport Source: Ensembl
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

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