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Mouse Anti-CLINT1 Recombinant Antibody (6G10) (V2LY-1206-LY235)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
6G10
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
Human recombinant protein fragment corresponding to amino acids 1-290 of human CLINT1.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/ml
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Clathrin Interactor 1
Entrez Gene ID
Human9685
Mouse216705
Rat360515
UniProt ID
HumanQ14677
MouseQ99KN9
RatQ6DGF2
Function
Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.
Biological Process
Clathrin coat assembly Source: Ensembl
Endocytosis Source: GO_Central
Post-Golgi vesicle-mediated transport Source: Reactome
Cellular Location
Cytoplasm; Perinuclear region; Clathrin-coated vesicle. Found throughout the cell, with the exception of the cell surface. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the trans-Golgi network.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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