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Mouse Anti-CLPS Recombinant Antibody (8A8) (CBMAB-C9044-LY)

This product is antibody recognizes CLPS. The antibody 8A8 immunoassay techniques such as: ELISA, IP, WB.
See all CLPS antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
8A8
Antibody Isotype
IgG2a, κ
Application
ELISA, IP, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Colipase
Introduction
The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Entrez Gene ID
1208
UniProt ID
P04118
Alternative Names
Colipase; Colipase, Pancreatic; Pancreatic Colipase Preproprotein; Pancreatic Colipase;
Function
Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
Biological Process
Lipid catabolic process Source: UniProtKB-KW
Lipid digestion Source: Reactome
Lipid metabolic process Source: ProtInc
Response to bacterium Source: Ensembl
Response to food Source: GO_Central
Retinoid metabolic process Source: Reactome
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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