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Mouse Anti-CNKSR3 Recombinant Antibody (CBXC-0488) (CBMAB-C5452-CQ)

This product is a mouse antibody that recognizes CNKSR3. The antibody CBXC-0488 can be used for immunoassay techniques such as: ELISA, IP, WB.
See all CNKSR3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXC-0488
Antibody Isotype
IgG2b, κ
Application
ELISA, IP, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
CNKSR family member 3
Introduction
CNKSR3 (CNKSR Family Member 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include peroxidase activity and oxygen carrier activity. An important paralog of this gene is CNKSR2.
Entrez Gene ID
154043
UniProt ID
Q6P9H4
Alternative Names
CNKSR Family Member 3; Connector Enhancer Of KSR 3; CNK Homolog Protein 3; Maguin-Like Protein; MAGI1; CNK3;
Function
Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly of an ENaC-regulatory complex (ERC).
Biological Process
Negative regulation of ERK1 and ERK2 cascade Source: UniProtKB
Negative regulation of peptidyl-serine phosphorylation Source: UniProtKB
Positive regulation of sodium ion transport Source: UniProtKB
Cellular Location
Apical cell membrane; Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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