CNKSR3
CNKSR3 (CNKSR Family Member 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include peroxidase activity and oxygen carrier activity. An important paralog of this gene is CNKSR2.
Full Name
CNKSR family member 3
Function
Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly of an ENaC-regulatory complex (ERC).
Biological Process
Negative regulation of ERK1 and ERK2 cascade Source: UniProtKB
Negative regulation of peptidyl-serine phosphorylation Source: UniProtKB
Positive regulation of sodium ion transport Source: UniProtKB
Negative regulation of peptidyl-serine phosphorylation Source: UniProtKB
Positive regulation of sodium ion transport Source: UniProtKB
Cellular Location
Apical cell membrane; Cytoplasm
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Anti-CNKSR3 antibodies
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Target: CNKSR3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLNC-142
Application*: WB, E, IP
Target: CNKSR3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 1D7
Application*: IH, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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