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Mouse Anti-C5B-9 Recombinant Antibody (CBFYA-0216) (CBMAB-X0304-FY)


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Published Data
CBMAB-X0304-FY-1
Mouse Anti-C5B-9 Recombinant Antibody (CBFYA-0216) (CBMAB-X0304-FY) in IF
Representative immunofluorescence images of C5b-9 in the liver 2 hours after tumor cell injection. Scale bar, 10 µm. ...View More
Dai, B., Zhang, R., Qi, S., Liu, L., Zhang, X., Deng, D., ... & Zhang, Z. (2022). Intravital molecular imaging reveals that ROS-caspase-3-GSDME-induced cell punching enhances humoral immunotherapy targeting intracellular tumor antigens. Theranostics, 12(17), 7603.
CBMAB-X0304-FY-2
Mouse Anti-C5B-9 Recombinant Antibody (CBFYA-0216) (CBMAB-X0304-FY) in IHC
Expression of C5b-9 in kidney tissue was analyzed by IHC. Twenty-five μg/mouse sCD59-cys pretreatment is effective against the assembly of C5b-9. Magnification, ×400. All the scale bars represent 50 μm. ...View More
Wang, F., Huang, M., Wang, Y., Hong, Y., Zang, D., Yang, C., ... & Zhu, Q. (2022). Membrane attack complex C5b-9 promotes renal tubular epithelial cell pyroptosis in trichloroethylene-sensitized mice. Frontiers in pharmacology, 13, 877988.
CBMAB-X0304-FY-3
Mouse Anti-C5B-9 Recombinant Antibody (CBFYA-0216) (CBMAB-X0304-FY) in IF
SQ reduced IgG, C3, and C5b-9 deposition in glomeruli of PHN rats (magnification × 400). Kidney cryosections in each group were detected for IgG, C3, and C5b-9 by immunofluorescence staining. ...View More
Wang, X., Liu, J., Tian, R., Zheng, B., Li, C., Huang, L., ... & Xu, P. (2021). Sanqi oral solution mitigates proteinuria in rat passive heymann nephritis and blocks podocyte apoptosis via Nrf2/HO-1 pathway. Frontiers in pharmacology, 12, 727874.

Summary

Host Animal
Mouse
Specificity
Rat, Mouse
Clone
CBFYA-0216
Antibody Isotype
IgG1, κ
Application
WB, IF

Basic Information

Immunogen
C5b-9 of rat origin.
Host Species
Mouse
Specificity
Rat, Mouse
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IF(ICC)1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
0.09% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Complement C5
Introduction
Likely component of the classical pathway of the complement cascade; may be involved with tissue injury associated with ischemia or sepsis; may be a component of the membrane attack complex.
Entrez Gene ID
362119
Alternative Names
Hc; C5a; RGD1561905
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For research use only. Not intended for any clinical use.

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