Mouse Anti-CNKSR3 Recombinant Antibody (CBLNC-142) (V2LY-1206-LY425)

Name: Mouse Anti-CNKSR3 Recombinant Antibody (CBLNC-142)
SKU: V2LY-1206-LY425
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBLNC-142

Application

WB, ELISA, IP

Immunogen

CNKSR3 (366 a.a. ~ 464 a.a) partial recombinant protein.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

CNKSR family member 3

Entrez Gene ID

154043

UniProt ID

Q6P9H4

Function

Involved in transepithelial sodium transport. Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression. Acts as a scaffold protein coordinating the assembly of an ENaC-regulatory complex (ERC).

Biological Process

Negative regulation of ERK1 and ERK2 cascade Source: UniProtKB
Negative regulation of peptidyl-serine phosphorylation Source: UniProtKB
Positive regulation of sodium ion transport Source: UniProtKB

Cellular Location

Apical cell membrane; Cytoplasm

Jin, L., Wang, T., Jiang, S., Chen, M., Zhang, R., Hu, C., ... & Liu, Z. (2017). The association of a genetic variant in SCAF8-CNKSR3 with diabetic kidney disease and diabetic retinopathy in a Chinese population. Journal of Diabetes Research, 2017.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-CNKSR3 Recombinant Antibody (1D7) (CAT#: V2LY-1206-LY424)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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