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Mouse Anti-CNPY3 Recombinant Antibody (F-6) (CBMAB-P0233-YC)

Provided herein is a Mouse monoclonal antibody against Human Canopy FGF Signaling Regulator 3. The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all CNPY3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
F-6
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Canopy FGF Signaling Regulator 3
Introduction
CNPY3 (Canopy FGF Signaling Regulator 3) is a protein coding gene. Diseases associated with CNPY3 include Swayback. Among its related pathways are Innate Immune System and Activated TLR4 signalling. Gene Ontology annotations related to this gene include receptor binding. An important paralog of the gene is CNPY4.
Entrez Gene ID
UniProt ID
Alternative Names
CAG4A; ERDA5; PRAT4A; TNRC5
Function
Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity).
Biological Process
Innate immune response Source: UniProtKB-KW
Toll-like receptor signaling pathway Source: Reactome
Cellular Location
Endoplasmic reticulum
Involvement in disease
Developmental and epileptic encephalopathy 60 (DEE60):
A form of epileptic encephalopathy, a heterogeneous group of severe childhood onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent. DEE60 is an autosomal recessive condition characterized by onset of seizures in the first months of life.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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