CNPY3

CNPY3 (Canopy FGF Signaling Regulator 3) is a protein coding gene. Diseases associated with CNPY3 include Swayback. Among its related pathways are Innate Immune System and Activated TLR4 signalling. Gene Ontology annotations related to this gene include receptor binding. An important paralog of the gene is CNPY4.

Canopy FGF Signaling Regulator 3

Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity).

Innate immune response Source: UniProtKB-KW
Toll-like receptor signaling pathway Source: Reactome

Endoplasmic reticulum

Developmental and epileptic encephalopathy 60 (DEE60):
A form of epileptic encephalopathy, a heterogeneous group of severe childhood onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent. DEE60 is an autosomal recessive condition characterized by onset of seizures in the first months of life.