CNPY3

CNPY3 (Canopy FGF Signaling Regulator 3) is a protein coding gene. Diseases associated with CNPY3 include Swayback. Among its related pathways are Innate Immune System and Activated TLR4 signalling. Gene Ontology annotations related to this gene include receptor binding. An important paralog of the gene is CNPY4.
Full Name
Canopy FGF Signaling Regulator 3
Function
Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity).
Biological Process
Innate immune response Source: UniProtKB-KW
Toll-like receptor signaling pathway Source: Reactome
Cellular Location
Endoplasmic reticulum
Involvement in disease
Developmental and epileptic encephalopathy 60 (DEE60):
A form of epileptic encephalopathy, a heterogeneous group of severe childhood onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent. DEE60 is an autosomal recessive condition characterized by onset of seizures in the first months of life.
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Anti-CNPY3 antibodies

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Mouse Recombinant CNPY3 protein, His Tag (V2LY-0526-LY8138)

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Target: CNPY3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-272
Tag: His Tag
Datasheet SDS

Mouse Recombinant CNPY3 protein, hFc Tag (V2LY-0526-LY8137)

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Target: CNPY3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-272
Tag: hFc Tag
Datasheet SDS

Human Recombinant CNPY3 protein, His Tag (V2LY-0526-LY3299)

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Target: CNPY3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-274
Tag: His Tag
Datasheet SDS

Human Recombinant CNPY3 protein, hFc Tag (V2LY-0526-LY3298)

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Target: CNPY3
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-274
Tag: hFc Tag
Datasheet SDS

Mouse Anti-CNPY3 Recombinant Antibody (P0233) (V2LY-1206-LY496)

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Target: CNPY3
Host: Mouse
Antibody Isotype: , Human, Mouse, Rat,
Specificity: Human, Mouse, Rat
Clone: , Human, Mouse, Rat,
Application*: Human, Mouse, Rat
Functional Assay
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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