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Mouse Anti-CAPZB Recombinant Antibody (CBYY-C0944) (CBMAB-C2381-YY)

This product is mouse antibody that recognizes CAPZB. The antibody CBYY-C0944 can be used for immunoassay techniques such as: ELISA, WB
See all CAPZB antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C0944
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Recombinant protein corresponding to aa192-272 from human CAPZB with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Preservative
PBS, pH 7.4
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
capping protein (actin filament) muscle Z-line, beta
Entrez Gene ID
832
UniProt ID
P47756
Alternative Names
Caspase 3; Caspase 3, Apoptosis-Related Cysteine Peptidase; Caspase 3, Apoptosis-Related Cysteine Protease; SREBP Cleavage Activity 1; Cysteine Protease CPP32; Protein Yama; EC 3.4.22.56; Apopain; CASP-3;
Function
F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Biological Process
Actin cytoskeleton organization Source: InterPro
Antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
Barbed-end actin filament capping Source: GO_Central
Blood coagulation Source: Reactome
Cell morphogenesis Source: GO_Central
Cytoskeleton organization Source: UniProtKB
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: Reactome
Negative regulation of filopodium assembly Source: GO_Central
Regulation of cell morphogenesis Source: UniProtKB
Regulation of lamellipodium assembly Source: GO_Central
Cellular Location
Cytoskeleton; Sarcomere
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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