CAPZB

CAPZB is a member of the F-actin capping protein family. This gene encodes the beta subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq]
Full Name
capping protein (actin filament) muscle Z-line, beta
Function
F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Biological Process
Actin cytoskeleton organization Source: InterPro
Antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
Barbed-end actin filament capping Source: GO_Central
Blood coagulation Source: Reactome
Cell morphogenesis Source: GO_Central
Cytoskeleton organization Source: UniProtKB
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: Reactome
Negative regulation of filopodium assembly Source: GO_Central
Regulation of cell morphogenesis Source: UniProtKB
Regulation of lamellipodium assembly Source: GO_Central
Cellular Location
Cytoskeleton; Sarcomere
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Anti-CAPZB antibodies

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Mouse Anti-CAPZB Recombinant Antibody (CBYY-C0944) (CBMAB-C2381-YY)

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Target: CAPZB
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Dog, Chicken
Clone: CBYY-C0944
Application*: IP, WB
Datasheet SDS

Rabbit Anti-CAPZB Recombinant Antibody (CBXC-0066) (CBMAB-C5067-CQ)

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Target: CAPZB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXC-0066
Application*: WB
Datasheet SDS

Mouse Anti-CAPZB Recombinant Antibody (4H8) (CBMAB-C7074-LY)

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Target: CAPZB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4H8
Application*: E, WB
Datasheet SDS

Mouse Anti-CAPZB Recombinant Antibody (1H1) (CBMAB-C4212-LY)

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Target: CAPZB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1H1
Application*: WB, P, E
Datasheet SDS

Human CAPZB ELISA Kit (2) (V2LY-0626-LY3888)

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Target: CAPZB
Sensitivity: 0.005 ng/mL
Detection Range: 0.01-2 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Human CAPZB ELISA Kit (V2LY-0626-LY3491)

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Target: CAPZB
Sensitivity: 0.04 ng/mL
Detection Range: 0.1-40 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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