Mouse Anti-CNPY3 Recombinant Antibody (P0233) (V2LY-1206-LY496)

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Basic Information

Host Animal
Mouse
Clone
, Human, Mouse, Rat,
Application
HumaNeutralization, MousELISA, Rat
Immunogen
, Human, Mouse, Rat,
Host Species
, Human, Mouse, Rat,
Specificity
Human, Mouse, Rat
Antibody Isotype
, Human, Mouse, Rat,
Modification
, Human, Mouse, Rat,
Clonality
, Human, Mouse, Rat,
Application Notes
, Human, Mouse, Rat,
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Endotoxin
, Human, Mouse, Rat,
Format
, Human, Mouse, Rat,
Buffer
, Human, Mouse, Rat,
Preservative
, Human, Mouse, Rat,
Concentration
, Human, Mouse, Rat,
Purity
, Human, Mouse, Rat,
Storage
, Human, Mouse, Rat,
Epitope
, Human, Mouse, Rat,
More Infomation

Target

Full Name
Canopy FGF Signaling Regulator 3
Entrez Gene ID
Human10695
Mouse72029
Rat685174
UniProt ID
HumanQ9BT09
MouseQ9DAU1
RatB2RYF8
Function
Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity).
Biological Process
Innate immune response Source: UniProtKB-KW
Toll-like receptor signaling pathway Source: Reactome
Cellular Location
Endoplasmic reticulum
Involvement in disease
Developmental and epileptic encephalopathy 60 (DEE60):
A form of epileptic encephalopathy, a heterogeneous group of severe childhood onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent. DEE60 is an autosomal recessive condition characterized by onset of seizures in the first months of life.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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