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Rabbit Anti-COA7 Recombinant Antibody (CBWJC-2889) (CBMAB-C4016WJ)

This product is a Rabbit antibody that recognizes COA7. This antibody CBWJC-2889 can be used for immunoassay techniques such as: WB.
See all COA7 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Human
Clone
CBWJC-2889
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Mouse, Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
0.746 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cytochrome C Oxidase Assembly Factor 7 (Putative)
Introduction
COA7 (Cytochrome C Oxidase Assembly Factor 7 (Putative)) is a Protein Coding gene. Diseases associated with COA7 include Mitochondrial Complex Iv Deficiency.
Entrez Gene ID
Human65260
Mouse69893
UniProt ID
HumanQ96BR5
MouseQ921H9
Alternative Names
Cytochrome C Oxidase Assembly Factor 7 (Putative); Cytochrome C Oxidase Assembly Factor 7; Respiratory Chain Assembly Factor 1; Sel1 Repeat-Containing Protein 1; Beta-Lactamase Hcp-Like Protein; Respiratory Chain Assembly 1; Sel1 Repeat Containing 1;
Function
Required for assembly of mitochondrial respiratory chain complex I and complex IV.
Cellular Location
Mitochondrion intermembrane space. The import in the mitochondrion intermembrane space is mediated by CHCHD4/MIA40.
Involvement in disease
Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 3 (SCAN3):
A form of spinocerebellar ataxia, a clinically and genetically heterogeneous group of cerebellar disorders due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAN3 is an autosomal recessive disorder characterized by onset in the first decade of slowly progressive distal muscle weakness and atrophy and distal sensory impairment due to an axonal peripheral neuropathy. Affected individuals have gait disturbances and sometimes manual dexterity difficulties, as well as cerebellar ataxia associated with cerebellar atrophy on brain imaging.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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