Sign in or Register   Sign in or Register
  |  

Mouse Anti-COL6A2 Recombinant Antibody (2C5-F2) (CBMAB-C4804-LY)

This product is antibody recognizes COL6A2. The antibody 2C5-F2 immunoassay techniques such as: ELISA, IHC-P, WB.
See all COL6A2 antibodies
Published Data
Fig.1 Immunoblotting was performed for COL6A2 on occipital lobe tissue lysates of non-demented controls, AD cases and CAA cases.
...View More
Fig.2 COL6A2 immunoreactivity is hardly observed in the control and AD cases
...View More

Summary

Host Animal
Mouse
Specificity
Human
Clone
2C5-F2
Antibody Isotype
IgG2a
Application
ELISA, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Collagen Type VI Alpha 2 Chain
Introduction
COL6A2 (Collagen Type VI Alpha 2 Chain) is a Protein Coding gene. Diseases associated with COL6A2 include Ullrich Congenital Muscular Dystrophy 1 and Myosclerosis, Autosomal Recessive. Among its related pathways are Integrin Pathway and ERK Signaling.

An important paralog of this gene is COL6A1.
Entrez Gene ID
1292
UniProt ID
P12110
Alternative Names
Collagen Type VI Alpha 2 Chain; Human MRNA For Collagen VI Alpha-2 C-Terminal Globular Domain; Collagen VI, Alpha-2 Polypeptide; Collagen Alpha-2(VI) Chain; Collagen, Type VI, Alpha 2; Collagen Type VI Alpha 2; BTHLM1; PP3610; UCMD1;
Function
Collagen VI acts as a cell-binding protein.
Biological Process
Cell adhesion Source: UniProtKB-KW
Collagen fibril organization Source: Reactome
Extracellular matrix organization Source: Reactome
Response to glucose Source: Ensembl
Cellular Location
Extracellular matrix; Membrane. Recruited on membranes by CSPG4.
Involvement in disease
Bethlem myopathy 1 (BTHLM1):
A benign proximal myopathy characterized by early childhood onset and joint contractures most frequently affecting the elbows and ankles.
Ullrich congenital muscular dystrophy 1 (UCMD1):
A congenital myopathy characterized by muscle weakness and multiple joint contractures, generally noted at birth or early infancy. The clinical course is more severe than in Bethlem myopathy.
Myosclerosis autosomal recessive (MYOSAR):
A condition characterized by chronic inflammation of skeletal muscle with hyperplasia of the interstitial connective tissue. The clinical picture includes slender muscles with firm 'woody' consistency and restriction of movement of many joints because of muscle contractures.
PTM
Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-COL6A2 Recombinant Antibody (2C5-F2)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare