Sign in or Register   Sign in or Register
  |  

Rabbit Anti-COL6A2 Recombinant Antibody (EG777) (CBMAB-EN932-LY)

The product is antibody recognizes COL6A2. The antibody EG777 immunoassay techniques such as: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000.
See all COL6A2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse
Clone
EG777
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human Collagen VI α2.
Specificity
Human, Mouse
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Collagen Type VI Alpha 2 Chain
Introduction
COL6A2 (Collagen Type VI Alpha 2 Chain) is a Protein Coding gene. Diseases associated with COL6A2 include Ullrich Congenital Muscular Dystrophy 1 and Myosclerosis, Autosomal Recessive. Among its related pathways are Integrin Pathway and ERK Signaling. An important paralog of this gene is COL6A1.
Entrez Gene ID
Human1292
Mouse12834
UniProt ID
HumanP12110
MouseQ02788
Alternative Names
Collagen Type VI Alpha 2 Chain; Human MRNA For Collagen VI Alpha-2 C-Terminal Globular Domain; Collagen VI, Alpha-2 Polypeptide; Collagen Alpha-2(VI) Chain; Collagen, Type VI, Alpha 2; Collagen Type VI Alpha 2; BTHLM1; PP3610; UCMD1;
Function
Collagen VI acts as a cell-binding protein.
Biological Process
Cell adhesion Source: UniProtKB-KW
Collagen fibril organization Source: Reactome
Extracellular matrix organization Source: Reactome
Response to glucose Source: Ensembl
Cellular Location
Extracellular matrix; Membrane. Recruited on membranes by CSPG4.
Involvement in disease
Bethlem myopathy 1 (BTHLM1):
A benign proximal myopathy characterized by early childhood onset and joint contractures most frequently affecting the elbows and ankles.
Ullrich congenital muscular dystrophy 1 (UCMD1):
A congenital myopathy characterized by muscle weakness and multiple joint contractures, generally noted at birth or early infancy. The clinical course is more severe than in Bethlem myopathy.
Myosclerosis autosomal recessive (MYOSAR):
A condition characterized by chronic inflammation of skeletal muscle with hyperplasia of the interstitial connective tissue. The clinical picture includes slender muscles with firm 'woody' consistency and restriction of movement of many joints because of muscle contractures.
PTM
Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-COL6A2 Recombinant Antibody (EG777)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare