Rabbit Anti-COMMD8 Recombinant Antibody (CBFYC-2090) (CBMAB-C2156-FY)

This product is rabbit antibody that recognizes COMMD8. The antibody CBFYC-2090 can be used for immunoassay techniques such as: ELISA.
See all COMMD8 antibodies

Summary

Host Animal

Rabbit

Specificity

Human

Clone

CBFYC-2090

Antibody Isotype

IgG

Application

ELISA

Basic Information

Immunogen

Recombinant Human COMMD8 Protein

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

COMM Domain Containing 8

Introduction

COMMD8 (COMM Domain Containing 8) is a Protein Coding gene.

Entrez Gene ID

54951

UniProt ID

Q9NX08

Alternative Names

COMM Domain Containing 8

Function

May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237).

May down-regulate activation of NF-kappa-B (PubMed:15799966).

Cellular Location

Cytoplasm; Nucleus

References

Kempiński, K., Romantowski, J., Maciejewska, A., Pawłowski, R., Chełmińska, M., Jassem, E., & Niedoszytko, M. (2020). COMMD8 changes expression during initial phase of wasp venom immunotherapy. The Journal of Gene Medicine, 22(11), e3243.

Zhang, R., Niu, Z., Pei, H., & Peng, Z. (2020). Long noncoding RNA LINC00657 induced by SP1 contributes to the non‐small cell lung cancer progression through targeting miR‐26b‐5p/COMMD8 axis. Journal of cellular physiology, 235(4), 3340-3349.

Wang, S., Wang, T., Liu, D., & Kong, H. (2020). LncRNA MALAT1 aggravates the progression of non-small cell lung cancer by stimulating the expression of COMMD8 via targeting miR-613. Cancer Management and Research, 12, 10735.

Nakai, A., Fujimoto, J., Miyata, H., Stumm, R., Narazaki, M., Schulz, S., ... & Suzuki, K. (2019). The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors. Journal of Experimental Medicine, 216(7), 1630-1647.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-COMMD8 Recombinant Antibody (CBLC170-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Datasheet
SDS
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