Mouse Anti-COMMD8 Recombinant Antibody (CBLC170-LY) (CBMAB-C11117-LY)

The product is antibody recognizes COMMD8. The antibody CBLC170-LY immunoassay techniques such as: WB, IP, IF, ELISA.
See all COMMD8 antibodies

Summary

Host Animal

Mouse

Specificity

Mouse, Rat

Clone

CBLC170-LY

Antibody Isotype

IgG

Application

WB, IP, IF, ELISA

Basic Information

Specificity

Mouse, Rat

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

COMM Domain Containing 8

Introduction

COMMD8 (COMM Domain Containing 8) is a Protein Coding gene.

Entrez Gene ID

Mouse	27784
Rat	289603

UniProt ID

Mouse	Q9CZG3
Rat	B0K015

Function

May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237).

May down-regulate activation of NF-kappa-B (PubMed:15799966).

Cellular Location

Cytoplasm; Nucleus

References

Kempiński, K., Romantowski, J., Maciejewska, A., Pawłowski, R., Chełmińska, M., Jassem, E., & Niedoszytko, M. (2020). COMMD8 changes expression during initial phase of wasp venom immunotherapy. The Journal of Gene Medicine, 22(11), e3243.

Zhang, R., Niu, Z., Pei, H., & Peng, Z. (2020). Long noncoding RNA LINC00657 induced by SP1 contributes to the non‐small cell lung cancer progression through targeting miR‐26b‐5p/COMMD8 axis. Journal of cellular physiology, 235(4), 3340-3349.

Wang, S., Wang, T., Liu, D., & Kong, H. (2020). LncRNA MALAT1 aggravates the progression of non-small cell lung cancer by stimulating the expression of COMMD8 via targeting miR-613. Cancer Management and Research, 12, 10735.

Nakai, A., Fujimoto, J., Miyata, H., Stumm, R., Narazaki, M., Schulz, S., ... & Suzuki, K. (2019). The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors. Journal of Experimental Medicine, 216(7), 1630-1647.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Rabbit Anti-COMMD8 Recombinant Antibody (CBFYC-2090)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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SDS
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Second antibody and isotype control

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