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Mouse Anti-COQ7 Recombinant Antibody (CBYY-C1002) (CBMAB-C2439-YY)

This product is mouse antibody that recognizes CAT5. The antibody CBYY-C1002 can be used for immunoassay techniques such as: ELISA, WB
See all COQ7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C1002
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Immunogen
Recombinant Human COQ7 protein. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human COQ7
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Affinity purified
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Coenzyme Q7, Hydroxylase
Entrez Gene ID
10229
UniProt ID
Q99807
Function
Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
Biological Process
Determination of adult lifespan Source: GO_Central
Negative regulation of transcription by RNA polymerase II Source: WormBase
Positive regulation of transcription by RNA polymerase II Source: WormBase
Regulation of gene expression Source: GO_Central
Regulation of reactive oxygen species metabolic process Source: WormBase
Ubiquinone biosynthetic process Source: GO_Central
Cellular Location
Mitochondrion inner membrane
Involvement in disease
Coenzyme Q10 deficiency, primary, 8 (COQ10D8):
An autosomal recessive disorder resulting from mitochondrial dysfunction and characterized by decreased levels of coenzyme Q10. Patients manifest neonatal lung hypoplasia, contractures, early infantile hypertension and cardiac hypertrophy, secondary to prenatal kidney dysplasia, with neonatal and infantile renal dysfunction. Clinical features also include progressive peripheral neuropathy, muscular hypotonia and atrophy, and mild psychomotor delay with hearing and visual impairment.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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