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Mouse Anti-CRP Recombinant Antibody (CBYY-C2872) (CBMAB-C4315-YY)

This product is mouse antibody that recognizes CRP. The antibody CBYY-C2872 can be used for immunoassay techniques such as: ELISA
See all CRP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C2872
Antibody Isotype
IgG
Application
ELISA

Basic Information

Immunogen
E.coli-derived recombinant human C-Reactive Protein (CRP)
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Preservative
PBS
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
C-Reactive Protein
Entrez Gene ID
1401
UniProt ID
P02741
Alternative Names
Cleavage And Polyadenylation Specific Factor 4; Cleavage And Polyadenylation Specificity Factor 30 KDa Subunit; Cleavage And Polyadenylation Specific Factor 4, 30kDa; NS1 Effector Domain-Binding Protein 1; CPSF 30 KDa Subunit; No Arches Homolog; CPSF30;
Function
Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
Biological Process
Acute-phase response Source: BHF-UCL
Complement activation, classical pathway Source: GO_Central
Defense response to Gram-positive bacterium Source: BHF-UCL
Inflammatory response Source: ProtInc
Innate immune response Source: GO_Central
Negative regulation by host of viral process Source: GO_Central
Negative regulation of lipid storage Source: BHF-UCL
Negative regulation of macrophage derived foam cell differentiation Source: BHF-UCL
Negative regulation of mononuclear cell proliferation Source: CACAO
Opsonization Source: BHF-UCL
Positive regulation of gene expression Source: AgBase
Positive regulation of superoxide anion generation Source: AgBase
Regulation of interleukin-8 production Source: UniProtKB
Vasoconstriction Source: GO_Central
Cellular Location
Secreted

Luo, X., Zhou, W., Yan, X., Guo, T., Wang, B., Xia, H., ... & Yang, W. (2020). Prognostic value of C-reactive protein in patients with coronavirus 2019. Clinical Infectious Diseases, 71(16), 2174-2179.

Wang, G., Wu, C., Zhang, Q., Wu, F., Yu, B., Lv, J., ... & Zhong, Y. (2020, May). C-reactive protein level may predict the risk of COVID-19 aggravation. In Open forum infectious diseases (Vol. 7, No. 5, p. ofaa153). US: Oxford University Press.

Pathak, A., & Agrawal, A. (2019). Evolution of C-reactive protein. Frontiers in immunology, 10, 943.

Sproston, N. R., & Ashworth, J. J. (2018). Role of C-reactive protein at sites of inflammation and infection. Frontiers in immunology, 9, 754.

Ticinesi, A., Lauretani, F., Nouvenne, A., Porro, E., Fanelli, G., Maggio, M., & Meschi, T. (2017). C-reactive protein (CRP) measurement in geriatric patients hospitalized for acute infection. European Journal of Internal Medicine, 37, 7-12.

Nehring, S. M., & Patel, B. C. (2017). C reactive protein (CRP).

Moutachakkir, M., Baraou, A., Boukhira, A., & Chellak, S. (2017, April). Immunoanalytical characteristics of C-reactive protein and high sensitivity C-reactive protein. In Annales de biologie clinique (Vol. 75, No. 2, pp. 225-229).

Köhler-Forsberg, O., Buttenschøn, H. N., Tansey, K. E., Maier, W., Hauser, J., Dernovsek, M. Z., ... & Mors, O. (2017). Association between C-reactive protein (CRP) with depression symptom severity and specific depressive symptoms in major depression. Brain, behavior, and immunity, 62, 344-350.

Stirling, A. D., Moran, N. R., Kelly, M. E., Ridgway, P. F., & Conlon, K. C. (2017). The predictive value of C-reactive protein (CRP) in acute pancreatitis–is interval change in CRP an additional indicator of severity?. Hpb, 19(10), 874-880.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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