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Mouse Anti-CSTF2 Antibody (1A11) (CBMAB-0247-YC)

Provided herein are mouse monoclonal antibodies against Human CSTF2. The antibody clone 1A11 can be used for immunoassay techniques, such as IP and MA.
See all CSTF2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1A11
Antibody Isotype
IgG2a
Application
IP, MA

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cleavage Stimulation Factor Subunit 2
Introduction
CSTF2 (cleavage stimulation factor subunit 2) is a nuclear protein with an RRM (RNA recognition motif) domain. CSTF2 is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, CSTF2 binds GU-rich elements within the 3'-untranslated region of mRNAs.
Entrez Gene ID
UniProt ID
Alternative Names
CstF-64
Function
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity).
Biological Process
mRNA 3'-end processing Source: Reactome
mRNA polyadenylation Source: InterPro
mRNA splicing, via spliceosome Source: Reactome
Pre-mRNA cleavage required for polyadenylation Source: GO_Central
Termination of RNA polymerase II transcription Source: Reactome
tRNA splicing, via endonucleolytic cleavage and ligation Source: Reactome
Cellular Location
Nucleus. Localized with DDX1 in cleavage bodies.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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