Sign in or Register   Sign in or Register
  |  

Mouse Anti-CTNND2 Recombinant Antibody (CBYY-C2302) (CBMAB-C3740-YY)

This product is mouse antibody that recognizes CTNND2. The antibody CBYY-C2302 can be used for immunoassay techniques such as: ELISA, WB
See all CTNND2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C2302
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein A purified
Preservative
PBS, pH 7.2
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
Entrez Gene ID
1501
UniProt ID
Q9UQB3
Alternative Names
CUE Domain Containing 1;
Function
Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses (PubMed:25807484).

Involved in the regulation of Wnt signaling (PubMed:25807484).

It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation (By similarity).

Functions as a transcriptional activator when bound to ZBTB33 (By similarity).

May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules.
Biological Process
Cell adhesion Source: ProtInc
Cell-cell adhesion Source: GO_Central
Cell-cell junction assembly Source: GO_Central
Dendritic spine morphogenesis Source: UniProtKB
Regulation of canonical Wnt signaling pathway Source: UniProtKB
Signal transduction Source: ProtInc
Synapse organization Source: UniProtKB
Wnt signaling pathway Source: UniProtKB-KW
Cellular Location
Nucleus; Adherens junction; Dendrite; Perikaryon
Involvement in disease
Defects in CTNND2, including deleterious missense and copy number variants (CNVs) are involved in autism, a complex multifactorial, pervasive developmental disorder characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Most individuals with autism also manifest moderate mental retardation.
PTM
O-glycosylated.
Phosphorylated by CDK5 (By similarity). Phosphorylated by GSK3B (PubMed:19706605).
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-CTNND2 Recombinant Antibody (CBYY-C2302)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare