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Rat Anti-CTSF Recombinant Antibody (CBXC-0997) (CBMAB-C3618-CQ)

This product is a rat antibody that recognizes CTSF. The antibody CBXC-0997 can be used for immunoassay techniques such as: WB, IP.
See all CTSF antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBXC-0997
Antibody Isotype
IgG2b
Application
WB, IP

Basic Information

Immunogen
NS0-derived recombinant mouse Cathepsin F, Ser20-Asn462, Accession # Q9WUT4
Specificity
Mouse
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
Lyophilized from PBS
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cathepsin E
Introduction
CTSF (Cathepsin F) is a Protein Coding gene. Diseases associated with CTSF include Ceroid Lipofuscinosis, Neuronal, 13 and Neuronal Ceroid Lipofuscinosis. Among its related pathways are Innate Immune System and MHC class II antigen presentation. Gene Ontology (GO) annotations related to this gene include cysteine-type endopeptidase activity and cysteine-type peptidase activity. An important paralog of this gene is CTSW.
Entrez Gene ID
56464
UniProt ID
Q9R013
Alternative Names
Cathepsin F; EC 3.4.22.41; CATSF; EC 3.4.22; CLN13;
Function
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Biological Process
Antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
Proteolysis Source: ProtInc
Proteolysis involved in cellular protein catabolic process Source: GO_Central
Cellular Location
Lysosome
Involvement in disease
Ceroid lipofuscinosis, neuronal, 13 (CLN13):
A form of neuronal ceroid lipofuscinosis characterized by adult onset of progressive cognitive decline and motor dysfunction leading to dementia and often early death. Some patients develop seizures. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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