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Rat Anti-CTSF Recombinant Antibody (6J10) (CBMAB-C8366-LY)

This product is antibody recognizes CTSF. The antibody 6J10 immunoassay techniques such as: WB.
See all CTSF antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
6J10
Antibody Isotype
IgG2
Application
WB

Basic Information

Immunogen
Mouse recombinant protein of Cathepsin F
Specificity
Mouse
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cathepsin E
Introduction
CTSE (Cathepsin E) is a Protein Coding gene. Diseases associated with CTSE include Gastric Adenocarcinoma and Rosai-Dorfman Disease. Among its related pathways are Innate Immune System and MHC class II antigen presentation. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and aspartic-type endopeptidase activity.
An important paralog of this gene is PGA3.
Entrez Gene ID
56464
UniProt ID
Q9R013
Function
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Biological Process
Antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
Proteolysis Source: ProtInc
Proteolysis involved in cellular protein catabolic process Source: GO_Central
Cellular Location
Lysosome
Involvement in disease
Ceroid lipofuscinosis, neuronal, 13 (CLN13):
A form of neuronal ceroid lipofuscinosis characterized by adult onset of progressive cognitive decline and motor dysfunction leading to dementia and often early death. Some patients develop seizures. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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