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Mouse Anti-CYB5R4 (AA 388-487) Recombinant Antibody (CBFYC-2555) (CBMAB-C2629-FY)

This product is mouse antibody that recognizes CYB5R4. The antibody CBFYC-2555 can be used for immunoassay techniques such as: ELISA, WB.
See all CYB5R4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-2555
Antibody Isotype
IgG2a, k
Application
ELISA, WB

Basic Information

Immunogen
Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 388-487

Target

Full Name
cytochrome b5 reductase 4
Introduction
CYB5R4 (Cytochrome B5 Reductase 4) is a Protein Coding gene. Diseases associated with CYB5R4 include Methemoglobin Reductase Deficiency and Methemoglobinemia. Among its related pathways are Metabolism and Amino sugar and nucleotide sugar metabolism. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and flavin adenine dinucleotide binding. An important paralog of this gene is CYB5R3.
Entrez Gene ID
51167
UniProt ID
Q7L1T6
Alternative Names
Cytochrome B5 Reductase 4; N-Terminal Cytochrome B5 And Cytochrome B5 Oxidoreductase Domain-Containing Protein; NADPH Cytochrome B5 Oxidoreductase; Flavohemoprotein B5/B5R; EC 1.6.2.2; Cb5/Cb5R
Function
NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin.
Biological Process
Bicarbonate transport Source: Reactome
Cell development Source: UniProtKB
Detection of oxygen Source: UniProtKB
Generation of precursor metabolites and energy Source: UniProtKB
Glucose homeostasis Source: UniProtKB
Insulin secretion Source: UniProtKB
Reactive oxygen species metabolic process Source: UniProtKB
Response to antibiotic Source: UniProtKB
Superoxide metabolic process Source: UniProtKB
Cellular Location
Endoplasmic reticulum. Soluble protein.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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