Rabbit Anti-DBX2 Monoclonal Antibody (EPR12633(B)) (CBMAB-0986-YC)

Provided herein is a rabbit monoclonal antibody against Human DotX2. The antibody, clone EPR12633(B), can be used for immunoassay techniques, such as WB.
See all DBX2 antibodies

Summary

Host Animal

Rabbit

Specificity

Human, Mouse, Rat

Clone

EPR12633(B)

Antibody Isotype

IgG

Application

Basic Information

Immunogen

Synthetic peptide within Human dbx2 aa 250 to the C-terminus (Cysteine residue).

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

>95%, as determined by SDS-PAGE analysis

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

DBX2

Introduction

Homeobox protein DBX2 is a protein that in humans is encoded by the DBX2 gene. DBX2 belongs to the H2.0 homeobox family.

Entrez Gene ID

Human	440097
Mouse	223843
Rat	541457

UniProt ID

Human	Q6ZNG2
Mouse	Q8BZD0
Rat	F1LRM4

Alternative Names

DBX2; developing brain homeobox protein 2; homeobox protein DBX2

Biological Process

Regulation of transcription by RNA polymerase II Source: GO_Central

Cellular Location

Nucleus

References

He, R., Zhang, X., & Ding, L. (2022). DBX2 promotes glioblastoma cell proliferation by regulating REST expression. Current pharmaceutical biotechnology.

Zhang, X., Wang, Y., Zhao, S., Qin, Q., Zhang, M., Jiang, Y., ... & Li, H. (2021). Low expression of developing brain homeobox 2 (Dbx2) may serve as a biomarker to predict poor prognosis in endometrial cancer. American Journal of Translational Research, 13(5), 4738.

Beccari, L., Jaquier, G., Lopez‐Delisle, L., Rodriguez‐Carballo, E., Mascrez, B., Gitto, S., ... & Duboule, D. (2021). Dbx2 regulation in limbs suggests inter TAD sharing of enhancers. Developmental Dynamics, 250(9), 1280-1299.

Hu, Y. T., Li, B. F., Zhang, P. J., Wu, D., Li, Y. Y., Li, Z. W., ... & Zhu, X. (2019). Dbx2 exhibits a tumor-promoting function in hepatocellular carcinoma cell lines via regulating Shh-Gli1 signaling. World Journal of Gastroenterology, 25(8), 923.

Lupo, G., Nisi, P. S., Esteve, P., Paul, Y. L., Novo, C. L., Sidders, B., ... & Rugg‐Gunn, P. J. (2018). Molecular profiling of aged neural progenitors identifies Dbx2 as a candidate regulator of age‐associated neurogenic decline. Aging Cell, 17(3), e12745.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

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Mouse Anti-DBX2 Antibody (1E5)

Mouse Anti-DBX2 Recombinant Antibody (R359.1.1D8)

Mouse Anti-DBX2 Recombinant Antibody (R359.1.1E4)

Mouse Anti-DBX2 Antibody (1E4)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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