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Rabbit Anti-DDX3Y Recombinant Antibody (EG941) (CBMAB-EN1117-LY)

The product is antibody recognizes DDX3Y. The antibody EG941 immunoassay techniques such as: IHC: 1:50~1:100 ELISA: 1:20000.
See all DDX3Y antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse
Clone
EG941
Antibody Isotype
IgG
Application
IHC: 1:50~1:100 ELISA: 1:20000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human DDX3Y.
Specificity
Human, Mouse
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
DEAD-Box Helicase 3, Y-Linked
Introduction
The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Entrez Gene ID
Human8653
Mouse26900
UniProt ID
HumanO15523
MouseQ62095
Alternative Names
DEAD-Box Helicase 3, Y-Linked; DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide, Y Chromosome; DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, Y-Linked; DEAD (Asp-Glu-Ala-Asp) Box Helicase 3, Y-Linked; DEAD Box Protein 3, Y-Chromosomal; DBY; ATP-Dependent RNA Helicase DDX3Y; EC 3.6.4.13; EC 3.6.1;
Function
Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity).
Biological Process
Cell differentiation Source: GO_Central
Gamete generation Source: GO_Central
Cellular Location
Nucleus; Cytoplasm. Shuttles between the nucleus and the cytoplasm in an XPO1-dependent manner.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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