Sign in or Register   Sign in or Register
  |  

Mouse Anti-DIEXF Recombinant Antibody (DEF3) (CBMAB-D0916-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Digestive Organ Expansion Factor Homolog (Zebrafish) (DIEXF). The antibody can be used for immunoassay techniques, such as IHC-P.
See all DIEXF antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
DEF3
Antibody Isotype
IgG
Application
IHC-P

Basic Information

Immunogen
Native defensins
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
digestive organ expansion factor homolog (zebrafish)
Introduction
DIEXF (Digestive Organ Expansion Factor Homolog (Zebrafish)) is a protein coding gene. Among its related pathways are Gene Expression and rRNA processing in the nucleus and cytosol. It has proved that the protein has U3 snoRNA binding.
Entrez Gene ID
27042
UniProt ID
Q68CQ4
Alternative Names
Digestive Organ Expansion Factor Homolog (Zebrafish); C1orf107; DEF; Digestive Organ Expansion Factor Homolog; Digestive-Organ Expansion Factor Homolog; Chromosome 1 Open Reading Frame 107; DJ434O14.5; UTP25;
Function
Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing (By similarity).

Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver (PubMed:25007945, PubMed:27657329, PubMed:23357851).

Also involved in the sympathetic neuronal development (By similarity).

Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53 (PubMed:23357851, PubMed:27657329).
Biological Process
Embryonic organ development Source: UniProtKB
Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: GO_Central
Positive regulation of embryonic development Source: UniProtKB
Protein catabolic process Source: UniProtKB
Protein destabilization Source: UniProtKB
Protein localization to nucleolus Source: UniProtKB
Cellular Location
Nucleolus
PTM
Phosphorylated. Phosphorylation is required to promote p53/TP53 degradation in the nucleolus which promotes cell cycle progression and liver development.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-DIEXF Recombinant Antibody (DEF3)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare