Sign in or Register   Sign in or Register
  |  

Rabbit Anti-DLX6 Monoclonal Antibody (EPR9474) (CBMAB-1032-YC)

Provided herein is a rabbit monoclonal antibody against Human DLX6. The antibody, clone EPR9474, can be used for immunoassay techniques, such as IP and WB.
See all DLX6 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EPR9474
Antibody Isotype
IgG
Application
IP, WB

Basic Information

Immunogen
Synthetic peptide corresponding to N terminal amino acids of Human Dlx6
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
distal-less homeobox 6
Introduction
The homeobox transcription factor family is comprised of at least 6 different members with roles in forebrain and craniofacial development. DLX6 is a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene.
Entrez Gene ID
Human1750
Mouse13396
Rat500023
UniProt ID
HumanP56179
MouseP70397
RatA0A096MIY0
Alternative Names
homeobox protein DLX-6; distal-less homeo box 6
Biological Process
Anatomical structure formation involved in morphogenesis Source: Ensembl
Cell differentiation Source: GO_Central
Embryonic limb morphogenesis Source: Ensembl
Epithelial cell differentiation Source: Ensembl
Head development Source: Ensembl
Inner ear morphogenesis Source: Ensembl
Nervous system development Source: ProtInc
Positive regulation of epithelial cell proliferation Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Roof of mouth development Source: Ensembl
Skeletal system development Source: ProtInc
Cellular Location
Nucleus

Mullen, R. D., Bellessort, B., Levi, G., & Behringer, R. D. (2022). Distal-less homeobox genes Dlx5/6 regulate Mulllerian duct regression. bioRxiv.

Kong, L., & Zhang, C. (2020). LncRNA DLX6-AS1 aggravates the development of ovarian cancer via modulating FHL2 by sponging miR-195-5p. Cancer Cell International, 20(1), 1-12.

Tian, S., Liu, J., Kong, S., & Peng, L. (2020). LncRNA DLX6-AS1 as a potential molecular biomarker in the clinicopathology and prognosis of various cancers: a meta-analysis. Bioscience Reports, 40(8).

Hu, X., Xiang, Z., Zhang, W., Yu, Z., Xin, X., Zhang, R., ... & Yuan, Q. (2020). Protective effect of DLX6-AS1 silencing against cerebral ischemia/reperfusion induced impairments. Aging (Albany NY), 12(22), 23096.

Fu, X., Tian, Y., Kuang, W., Wen, S., & Guo, W. (2019). Long non‑coding RNA DLX6‑AS1 silencing inhibits malignant phenotypes of gastric cancer cells. Experimental and therapeutic medicine, 17(6), 4715-4722.

Wang, X., Lin, Y., & Liu, J. (2019). Long non‑coding RNA DLX6‑AS1 promotes proliferation by acting as a ceRNA targeting miR‑199a in cervical cancer. Molecular medicine reports, 19(2), 1248-1255.

Zhang, X., Guo, H., Bao, Y., Yu, H., Xie, D., & Wang, X. (2019). Exosomal long non‑coding RNA DLX6‑AS1 as a potential diagnostic biomarker for non‑small cell lung cancer. Oncology letters, 18(5), 5197-5204.

Wang, M., Li, Y., Yang, Y., Liu, X., Zang, M., Li, Y., ... & Zhang, S. (2019). Long non‑coding RNA DLX6‑AS1 is associated with malignant progression and promotes proliferation and invasion in esophageal squamous cell carcinoma. Molecular medicine reports, 19(3), 1942-1950.

Zhang, N., Meng, X., Mei, L., Zhao, C., & Chen, W. (2019). LncRNA DLX6‐AS1 promotes tumor proliferation and metastasis in osteosarcoma through modulating miR‐641/HOXA9 signaling pathway. Journal of cellular biochemistry, 120(7), 11478-11489.

Huang, Y., Ni, R., Wang, J., & Liu, Y. (2019). Knockdown of lncRNA DLX6-AS1 inhibits cell proliferation, migration and invasion while promotes apoptosis by downregulating PRR11 expression and upregulating miR-144 in non-small cell lung cancer. Biomedicine & Pharmacotherapy, 109, 1851-1859.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-DLX6 Monoclonal Antibody (EPR9474)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare