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Mouse Anti-DNAL4 Recombinant Antibody (14i134) (CBMAB-D1330-YC)

Provided herein is a Mouse monoclonal antibody, which binds to Dynein Axonemal Light Chain 4 (DNAL4). The antibody can be used for immunoassay techniques, such as ELISA, FC, WB.
See all DNAL4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
14i134
Antibody Isotype
IgG
Application
ELISA, FC, WB

Basic Information

Immunogen
Recombinant protein corresponding to a.a.1-105 from human DNAL4 expressed in E. coli
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
dynein axonemal light chain 4
Introduction
DNAL4 is an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella.
Entrez Gene ID
10126
UniProt ID
O96015
Alternative Names
Dynein Axonemal Light Chain 4; Dynein, Axonemal, Light Polypeptide 4; Proliferation-Inducing Protein 27; Dynein Light Chain, Outer Arm 4; Dynein Light Chain 4, Axonemal; Proliferation-Inducing Gene 27; Dynein, Axonemal, Light 4; MRMV3; PIG27;
Function
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity).
Biological Process
Microtubule-based movement Source: Reactome
Positive regulation of ATP-dependent microtubule motor activity, plus-end-directed Source: GO_Central
Cellular Location
Cilium axoneme
Involvement in disease
Mirror movements 3 (MRMV3):
A disorder characterized by contralateral involuntary movements that mirror voluntary ones. While mirror movements are occasionally found in young children, persistence beyond the age of 10 is abnormal. Mirror movements occur more commonly in the upper extremities.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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