Sign in or Register   Sign in or Register
  |  

Mouse Anti-DSCC1 Recombinant Antibody (B12) (CBMAB-AP1949LY)


See all DSCC1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
B12
Antibody Isotype
IgG
Application
ELISA, IHC, WB

Basic Information

Immunogen
Peptide Sequence – KVYNSRRPIS (immunogen peptide is identical
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
DNA Replication And Sister Chromatid Cohesion 1
Introduction
CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).[supplied by OMIM, Dec 2009]
Entrez Gene ID
79075
UniProt ID
Q9BVC3
Alternative Names
DNA Replication And Sister Chromatid Cohesion 1; Defective In Sister Chromatid Cohesion Protein 1 Homolog; DCC1; Defective In Sister Chromatid Cohesion Homolog 1 (S. Cerevisiae); Defective In Sister Chromatid Cohesion 1 Homolog (S. Cerevisiae); Defective In Sister Chromatid Cohesion 1 Homolog; Sister Chromatid Cohesion Protein DCC1;
Research Area
Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3.
Biological Process
DNA duplex unwinding Source: GOC
DNA replication Source: UniProtKB-KW
Maintenance of mitotic sister chromatid cohesion Source: UniProtKB
Positive regulation of DNA-directed DNA polymerase activity Source: UniProtKB
Post-translational protein acetylation Source: UniProtKB
Regulation of DNA replication Source: UniProtKB
Cellular Location
Nucleus
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-DSCC1 Recombinant Antibody (B12)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare