Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-DYNC1LI1 Recombinant Antibody (CBFYC-2597) (V2LY-0425-LY1140)


See all DYNC1LI1 antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBFYC-2597
Antibody Isotype
IgA, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 5-23 at the N-terminus of human DNCLI1.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgA, κ
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
ELISA1:100-1:1,000
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Gelatin & PBS
Preservative
Sodium Azide
Concentration
0.2 mg/ml
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
DYNEIN CYTOPLASMIC 1 LIGHT INTERMEDIATE CHAIN 1
Entrez Gene ID
51143
UniProt ID
Q9Y6G9
Research Area
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
Biological Process
Cell cycle Source: UniProtKB-KW
Cell division Source: UniProtKB-KW
Microtubule-based movement Source: GO_Central
Microtubule cytoskeleton organization Source: GO_Central
Positive regulation of mitotic cell cycle spindle assembly checkpoint Source: UniProtKB
Cellular Location
Cytoplasm; Spindle pole; Kinetochore
PTM
Phosphorylated during mitosis but not in interphase.
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-DYNC1LI1 Recombinant Antibody (CBFYC-2597)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry