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Mouse Anti-EGFLAM Recombinant Antibody (CBFYE-0544) (CBMAB-E0909-FY)

This product is mouse antibody that recognizes EGFLAM. The antibody CBFYE-0544 can be used for immunoassay techniques such as: ELISA, WB.
See all EGFLAM antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYE-0544
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
EGF Like, Fibronectin Type III And Laminin G Domains
Introduction
EGFLAM (EGF Like, Fibronectin Type III And Laminin G Domains) is a Protein Coding gene. Diseases associated with EGFLAM include Adiaspiromycosis. Gene Ontology (GO) annotations related to this gene include calcium ion binding and glycosaminoglycan binding. An important paralog of this gene is AGRN.
Entrez Gene ID
UniProt ID
Alternative Names
EGF Like, Fibronectin Type III And Laminin G Domains; EGF-Like, Fibronectin Type-III And Laminin G-Like Domain-Containing Protein; Agrin-Like Protein; Pikachurin; AGRINL; AGRNL; PIKA; EGF-Like, Fibronectin Type III And Laminin G Domains; Agrin-Like
Research Area
Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness (By similarity).
Biological Process
Animal organ morphogenesis Source: GO_Central
Extracellular matrix organization Source: Ensembl
Peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan Source: Ensembl
Positive regulation of cell-substrate adhesion Source: Ensembl
Tissue development Source: GO_Central
Cellular Location
Extracellular matrix; Synaptic cleft; Presynaptic active zone. Detected in the synaptic cleft of the ribbon synapse around the postsynaptic terminals of bipolar cells. Colocalizes with BSN, CTBP2 and DAG1 in photoreceptor synaptic terminals.
PTM
O-glycosylated; contains chondroitin sulfate and heparan sulfate.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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