Mouse Anti-ERGIC3 Recombinant Antibody (CBFYE-1191) (CBMAB-E1761-FY)

This product is mouse antibody that recognizes ERGIC3. The antibody CBFYE-1191 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all ERGIC3 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Mouse, Rat, Human

Clone

CBFYE-1191

Application

WB, IP, IF, ELISA

Basic Information

Specificity

Mouse, Rat, Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

0.2 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Ergic And Golgi 3

Introduction

ERGIC3 (ERGIC And Golgi 3) is a Protein Coding gene. An important paralog of this gene is ERGIC2.

Entrez Gene ID

Human	51614
Mouse	66366
Rat	296306

UniProt ID

Human	Q9Y282
Mouse	Q9CQE7
Rat	D3ZU83

Alternative Names

ERGIC And Golgi 3; Serologically Defined Breast Cancer Antigen NY-BR-84; Serologically Defined Breast Cancer Antigen 84; C20orf47; SDBCAG84; Erv46; Endoplasmic Reticulum-Golgi Intermediate Compartment Protein 3; Endoplasmic Reticulum-Localized Protein ERp43

Research Area

Possible role in transport between endoplasmic reticulum and Golgi.

Biological Process

Endoplasmic reticulum to Golgi vesicle-mediated transport Source: GO_Central
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum Source: GO_Central

Cellular Location

Cis-Golgi network membrane; Endoplasmic reticulum membrane; Endoplasmic reticulum-Golgi intermediate compartment membrane. Cycles between the endoplasmic reticulum and the Golgi.

Topology

Cytoplasmic: 1-25
Helical: 26-46
Lumenal: 47-341
Helical: 342-362
Cytoplasmic: 363-383

References

Guan, L., Yang, Y., Liang, J., Miao, Y., Shang, A., Wang, B., ... & Ding, M. (2022). ERGIC2 and ERGIC3 regulate the ER‐to‐Golgi transport of gap junction proteins in metazoans. Traffic, 23(3), 140-157.

Liu, M., Zhao, Q., Zheng, X., Yang, L., Zhao, Y., Li, X., & Wu, M. (2022). Transcriptome changes in ERGIC3-knockdown hepatocellular carcinoma cells: ERGIC3 is a novel immune function related gene. PeerJ, 10, e13369.

Zhao, Q., Wu, M., Zheng, X., Yang, L., Zhang, Z., Li, X., & Chen, J. (2020). ERGIC3 silencing additively enhances the growth inhibition of BFA on lung adenocarcinoma cells. Current Cancer Drug Targets, 20(1), 67-75.

Yoo, W., Cho, E. B., Kim, S., & Yoon, J. B. (2019). The E3 ubiquitin ligase MARCH2 regulates ERGIC3-dependent trafficking of secretory proteins. Journal of Biological Chemistry, 294(28), 10900-10912.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Rabbit Anti-ERGIC3 Recombinant Antibody (EG1137)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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