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Mouse Anti-ESAM (AA 1-390) Recombinant Antibody (CBFYE-0261) (CBMAB-E0535-FY)

This product is mouse antibody that recognizes ESAM. The antibody CBFYE-0261 can be used for immunoassay techniques such as: ELISA.
See all ESAM antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYE-0261
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
ESAM full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen sequence: MISLPGPLVT NLLRFLFLGL SALAPPSRAQ LQLHLPANRL QAVEGGEVVL PAWYTLHGEV SSSQPWEVPF VMWFFKQKEK EDQVLSYING VTTSKPGVSL VYSMPSRNLS LRLEGLQEKD SGPYSCSVNV QDKQGKSRGH SIKTLELNVL VPPAPPSCRL QGVPHVGANV TLSCQSPRSK PAVQYQWDRQ LPSFQTFFAP ALDVIRGSLS LTNLSSSMAG VYVCKAHNEV GTAQCNVTLE VSTGPGAAVV AGAVVGTLVG LGLLAGLVLL YHRRGKALEE PANDIKEDAI APRTLPWPKS SDTISKNGTL SSVTSARALR PPHGPPRPGA LTPTPSLSSQ ALPSPRLPTT DGAHPQPISP IPGGVSSSGL SRMGAVPVMV PAQSQAGSLV
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-390

Target

Full Name
endothelial cell adhesion molecule
Introduction
ESAM (Endothelial Cell Adhesion Molecule) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Cell surface interactions at the vascular wall. An important paralog of this gene is IGSF11.
Entrez Gene ID
90952
UniProt ID
Q96AP7
Alternative Names
Endothelial Cell Adhesion Molecule; Endothelial Cell-Selective Adhesion Molecule; HUEL (C4orf1)-Interacting Protein; LP4791 Protein; 2310008D05Rik; W117m
Research Area
Can mediate aggregation most likely through a homophilic molecular interaction.
Biological Process
Bicellular tight junction assembly Source: ARUK-UCL
Cell-cell adhesion Source: ARUK-UCL
Cellular protein localization Source: ARUK-UCL
Homophilic cell adhesion via plasma membrane adhesion molecules Source: Ensembl
Maintenance of blood-brain barrier Source: ARUK-UCL
Regulation of actin cytoskeleton reorganization Source: ARUK-UCL
Regulation of actin filament polymerization Source: ARUK-UCL
Cellular Location
Cell membrane; Adherens junction; Tight junction
Topology
Extracellular: 30-248
Helical: 249-269
Cytoplasmic: 270-390
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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