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Rat Anti-ESAM (AA 30-248) Recombinant Antibody (CBFYE-1219) (CBMAB-E1789-FY)

This product is rat antibody that recognizes ESAM. The antibody CBFYE-1219 can be used for immunoassay techniques such as: WB.
See all ESAM antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBFYE-1219
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse ESAM, Gln30-Ser248
Specificity
Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, trehalose
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 30-248

Target

Full Name
endothelial cell adhesion molecule
Introduction
ESAM (Endothelial Cell Adhesion Molecule) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Cell surface interactions at the vascular wall. An important paralog of this gene is IGSF11.
Entrez Gene ID
69524
UniProt ID
Q925F2
Alternative Names
Esam1; W117m; 2310008D05Rik
Research Area
Can mediate aggregation most likely through a homophilic molecular interaction.
Biological Process
Bicellular tight junction assembly Source: ARUK-UCL
Cell-cell adhesion Source: ARUK-UCL
Cellular protein localization Source: ARUK-UCL
Homophilic cell adhesion via plasma membrane adhesion molecules Source: Ensembl
Maintenance of blood-brain barrier Source: ARUK-UCL
Regulation of actin cytoskeleton reorganization Source: ARUK-UCL
Regulation of actin filament polymerization Source: ARUK-UCL
Cellular Location
Cell membrane; Adherens junction; Tight junction
Topology
Extracellular: 30-248
Helical: 249-269
Cytoplasmic: 270-390
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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