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Mouse Anti-ESAM Recombinant Antibody (1E4) (CBMAB-A2713-LY)

The product is antibody recognizes ESAM. The antibody 1E4 immunoassay techniques such as: sELISA, ELISA.
See all ESAM antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1E4
Antibody Isotype
IgG2a, κ
Application
sELISA, ELISA

Basic Information

Immunogen
ESAM (AAH16868, 1 a.a. ~ 390 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
endothelial cell adhesion molecule
Entrez Gene ID
UniProt ID
Alternative Names
W117m
Research Area
Can mediate aggregation most likely through a homophilic molecular interaction.
Biological Process
Bicellular tight junction assembly Source: ARUK-UCL
Cell-cell adhesion Source: ARUK-UCL
Cellular protein localization Source: ARUK-UCL
Homophilic cell adhesion via plasma membrane adhesion molecules Source: Ensembl
Maintenance of blood-brain barrier Source: ARUK-UCL
Regulation of actin cytoskeleton reorganization Source: ARUK-UCL
Regulation of actin filament polymerization Source: ARUK-UCL
Cellular Location
Cell membrane; Adherens junction; Tight junction
Topology
Extracellular: 30-248
Helical: 249-269
Cytoplasmic: 270-390
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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