ESAM

ESAM (Endothelial Cell Adhesion Molecule) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Cell surface interactions at the vascular wall. An important paralog of this gene is IGSF11.
Full Name
endothelial cell adhesion molecule
Research Area
Can mediate aggregation most likely through a homophilic molecular interaction.
Biological Process
Bicellular tight junction assembly Source: ARUK-UCL
Cell-cell adhesion Source: ARUK-UCL
Cellular protein localization Source: ARUK-UCL
Homophilic cell adhesion via plasma membrane adhesion molecules Source: Ensembl
Maintenance of blood-brain barrier Source: ARUK-UCL
Regulation of actin cytoskeleton reorganization Source: ARUK-UCL
Regulation of actin filament polymerization Source: ARUK-UCL
Cellular Location
Cell membrane; Adherens junction; Tight junction
Topology
Extracellular: 30-248
Helical: 249-269
Cytoplasmic: 270-390
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Anti-ESAM antibodies

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Target: ESAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYE-1222
Application*: E
Target: ESAM
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E4
Application*: E
Target: ESAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYE-1223
Application*: E
Target: ESAM
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYE-1220
Application*: F
Target: ESAM
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1G8
Application*: E
Target: ESAM
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYE-1224
Application*: WB, IF
Target: ESAM
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBFYE-1221
Application*: WB
Target: ESAM
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYE-1219
Application*: IH
Target: ESAM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYE-0063
Application*: F
Target: ESAM
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: E0204
Application*: E
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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