Mouse Anti-ESD Recombinant Antibody (1E1) (CBMAB-A2715-LY)

The product is antibody recognizes ESD. The antibody 1E1 immunoassay techniques such as: WB, ELISA.
See all ESD antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

1E1

Antibody Isotype

IgG2a, κ

Application

WB, ELISA

Basic Information

Immunogen

ESD (NP_001975.1, 183 a.a. ~ 281 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Esterase D

Introduction

This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson's disease. [provided by RefSeq]

Entrez Gene ID

2098

UniProt ID

P10768

Research Area

Serine hydrolase involved in the detoxification of formaldehyde.

Biological Process

Formaldehyde catabolic process Source: InterPro

Cellular Location

Cytoplasm; Cytoplasmic vesicle

References

Yao, W., Yang, Y., Chen, X., Cui, X., Zhou, B., Zhao, B., ... & Miao, J. (2022). Activation of Esterase D by FPD5 Inhibits Growth of A549 Lung Cancer Cells via JAB1/p53 Pathway. Genes, 13(5), 786.

Chen, X., Su, L., Yang, Y., Qv, J., Wei, T., Cui, X., ... & Miao, J. (2021). A new activator of esterase D decreases blood cholesterol level through ESD/JAB1/ABCA1 pathway. Journal of Cellular Physiology, 236(6), 4750-4763.

Yang, Y., Chen, X., Yao, W., Cui, X., Li, N., Lin, Z., ... & Miao, J. (2021). Esterase D stabilizes FKBP25 to suppress mTORC1. Cellular & Molecular Biology Letters, 26(1), 1-16.

Chen, X., Yang, Y., Su, L., Cui, X., Shao, J., Liu, S., ... & Miao, J. (2020). Finding the mechanism of esterase D activation by a small molecule. Bioorganic & Medicinal Chemistry Letters, 30(11), 127150.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Antibody Pairs

ESD Matched Antibody Pair (390)

Related Products

ESD Matched Antibody Pair (390)

Mouse Anti-ESD Recombinant Antibody (CBFYE-1225)

Mouse Anti-ESD Recombinant Antibody (CAP724)

Mouse Anti-ESD (AA 183-281) Recombinant Antibody (CBFYE-1227)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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SDS
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