Mouse Anti-ESD Recombinant Antibody (CBFYE-1225) (CBMAB-E1795-FY)

This product is mouse antibody that recognizes ESD. The antibody CBFYE-1225 can be used for immunoassay techniques such as: WB, IHC-P, IF, FC.
See all ESD antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human, Mouse

Clone

CBFYE-1225

Antibody Isotype

IgG2c

Application

WB, IHC-P, IF, FC

Basic Information

Specificity

Human, Mouse

Antibody Isotype

IgG2c

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

TBS, pH7.4, 1% BSA, 40% glycerol

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Esterase D

Introduction

This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson's disease.

Entrez Gene ID

Human	2098
Mouse	13885

UniProt ID

Human	P10768
Mouse	Q9R0P3

Alternative Names

Esterase D; Esterase D/Formylglutathione Hydrolase; Methylumbelliferyl-Acetate Deacetylase; S-Formylglutathione Hydrolase; EC 3.1.2.12; FGH; Testicular Tissue Protein Li 66; Esterase 10; EC 3.1.1.56

Research Area

Serine hydrolase involved in the detoxification of formaldehyde.

Biological Process

Formaldehyde catabolic process Source: InterPro

Cellular Location

Cytoplasm; Cytoplasmic vesicle

References

Yao, W., Yang, Y., Chen, X., Cui, X., Zhou, B., Zhao, B., ... & Miao, J. (2022). Activation of Esterase D by FPD5 Inhibits Growth of A549 Lung Cancer Cells via JAB1/p53 Pathway. Genes, 13(5), 786.

Chen, X., Su, L., Yang, Y., Qv, J., Wei, T., Cui, X., ... & Miao, J. (2021). A new activator of esterase D decreases blood cholesterol level through ESD/JAB1/ABCA1 pathway. Journal of Cellular Physiology, 236(6), 4750-4763.

Yang, Y., Chen, X., Yao, W., Cui, X., Li, N., Lin, Z., ... & Miao, J. (2021). Esterase D stabilizes FKBP25 to suppress mTORC1. Cellular & Molecular Biology Letters, 26(1), 1-16.

Chen, X., Yang, Y., Su, L., Cui, X., Shao, J., Liu, S., ... & Miao, J. (2020). Finding the mechanism of esterase D activation by a small molecule. Bioorganic & Medicinal Chemistry Letters, 30(11), 127150.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Antibody Pairs

ESD Matched Antibody Pair (390)

Related Products

ESD Matched Antibody Pair (390)

Mouse Anti-ESD Recombinant Antibody (1E1)

Mouse Anti-ESD Recombinant Antibody (CAP724)

Mouse Anti-ESD (AA 183-281) Recombinant Antibody (CBFYE-1227)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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