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Mouse Anti-FAM120A Recombinant Antibody (CAP738) (CBMAB-AP2190LY)


See all FAM120A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CAP738
Antibody Isotype
IgG
Application
IF, IHC, WB

Basic Information

Immunogen
A synthetic peptide of human FAM120A
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Family With Sequence Similarity 120A
Introduction
FAM120A (Family With Sequence Similarity 120A) is a Protein Coding gene. Diseases associated with FAM120A include Myiasis and Retinitis Pigmentosa 59. An important paralog of this gene is FAM120C.
Entrez Gene ID
23196
UniProt ID
Q9NZB2
Alternative Names
Family With Sequence Similarity 120A; Oxidative Stress-Associated Src Activator; Oxidative Stess-Associated Src Activator; C9orf10; OSSA; Constitutive Coactivator Of PPAR-Gamma-Like Protein 1;
Research Area
May participate in mRNA transport in the cytoplasm (By similarity).

Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Cellular Location
Cell membrane; Cytoplasm. Translocates to plasma membrane upon ultraviolet exposure.
PTM
Arg-982 is dimethylated, probably to asymmetric dimethylarginine.
Phosphorylated on tyrosine by src family kinases upon ultraviolet exposure.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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