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Mouse Anti-FCRL4 Recombinant Antibody (CBYY-C0212) (CBMAB-C0612-YY)

This product is mouse antibody that recognizes FCRL4. The antibody CBYY-C0212 can be used for immunoassay techniques such as: FC
See all FCRL4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C0212
Antibody Isotype
IgG2b, κ
Application
FC

Basic Information

Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Preservative
PBS
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Fc Receptor Like 4
Entrez Gene ID
83417
UniProt ID
Q96PJ5
Alternative Names
CDC42 Binding Protein Kinase Beta; Myotonic Dystrophy Kinase-Related CDC42-Binding Kinase Beta; Myotonic Dystrophy Protein Kinase-Like Beta; DMPK-Like Beta; CDC42BP-Beta; EC 2.7.11.1; MRCK Beta; CDC42-Binding Protein Kinase Beta (DMPK-Like);
Research Area
May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response.
Biological Process
Adaptive immune response Source: UniProtKB-KW
Cell surface receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Involvement in disease
A chromosomal aberration involving FCRL4 is found in non-Hodgkin lymphoma (NHG). Translocation t(1;1)(p36.3; q21.1-2).
A chromosomal aberration involving FCRL4 is found in multiple myeloma (MM). Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.
Topology
Extracellular: 20-387
Helical: 388-408
Cytoplasmic: 409-515
PTM
Phosphorylated on cytoplasmic tyrosines upon activation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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