Sign in or Register   Sign in or Register
  |  

Mouse Anti-GMFB Recombinant Antibody (755) (CBMAB-AP2568LY)


See all GMFB antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
755
Antibody Isotype
IgG1
Application
ELISA, IF, IHC, WB

Basic Information

Immunogen
Fusion protein of GMF-beta
Specificity
Human, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Glia Maturation Factor Beta
Introduction
GMFB (Glia Maturation Factor Beta) is a Protein Coding gene. Among its related pathways are Signal transduction_Erk Interactions- Inhibition of Erk and Development Angiotensin activation of ERK. Gene Ontology (GO) annotations related to this gene include actin binding and growth factor activity. An important paralog of this gene is GMFG.
Entrez Gene ID
Human2764
Mouse63985
UniProt ID
HumanP60983
MouseQ9CQI3
Function
This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
Biological Process
Actin filament debranching Source: GO_Central
Negative regulation of Arp2/3 complex-mediated actin nucleation Source: GO_Central
Nervous system development Source: ProtInc
Protein phosphorylation Source: ProtInc
PTM
Phosphorylated; stimulated by phorbol ester.

Liu, C., Sun, W., Zhu, T., Shi, S., Zhang, J., Wang, J., ... & Lu, L. (2022). Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy. Redox Biology, 52, 102292.

Yin, G., Zeng, W., Li, R., Zeng, M., Chen, R., Liu, Y., ... & Wang, Y. (2022). Glia Maturation Factor-β Supports Liver Regeneration by Remodeling Actin Network to Enhance STAT3 Proliferative Signals. Cellular and Molecular Gastroenterology and Hepatology, 14(5), 1123-1145.

Zhu, T., Wang, T., Feng, Z., Gao, F., Zhang, J., Jin, C., ... & Lu, L. (2022). Glia Maturation Factor β as a Novel Independent Prognostic Biomarker and Potential Therapeutic Target of Kidney Renal Clear Cell Carcinoma. Frontiers in Oncology, 12.

Sun, W., Hu, C., Wang, T., Wang, J., Zhang, J., Gao, F., ... & Lu, L. (2021). Glia maturation factor beta as a novel biomarker and therapeutic target for hepatocellular carcinoma. Frontiers in Oncology, 11, 744331.

Teruya, K., Oguma, A., Arai, K., Nishizawa, K., Iwabuchi, S., Watanabe-Matsui, M., ... & Doh-Ura, K. (2021). Polymorphisms in glia maturation factor β gene are markers of cellulose ether effectiveness in prion-infected mice. Biochemical and biophysical research communications, 560, 105-111.

Wang, J., Awuti, M., Jiang, X., Zhang, J., Lyu, Y., Lu, L., & Xu, G. T. (2018). Effect of Glia Maturation Factor beta (GMFB) on Retinal Pigment Epithelium in Diabetic Retinopathy. Investigative Ophthalmology & Visual Science, 59(9), 3979-3979.

Xu, F. F., Zhang, Z. B., Wang, Y. Y., & Wang, T. H. (2018). Brain-derived glia maturation factor β participates in lung injury induced by acute cerebral ischemia by increasing ROS in endothelial cells. Neuroscience bulletin, 34, 1077-1090.

Yin, G., Du, M., Li, R., Li, K., Huang, X., Duan, D., ... & Wu, B. (2018). Glia maturation factor beta is required for reactive gliosis after traumatic brain injury in zebrafish. Experimental Neurology, 305, 129-138.

Fan, J., Fong, T., Chen, X., Chen, C., Luo, P., & Xie, H. (2018). Glia maturation factor-β: A potential therapeutic target in neurodegeneration and neuroinflammation. Neuropsychiatric disease and treatment, 495-504.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-GMFB Recombinant Antibody (755)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare