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Mouse Anti-GTF2E1 Antibody (2C12) (CBMAB-0424-YC)

Provided herein are mouse monoclonal antibodies against Human GTF2E1. The antibody clone 2C12 can be used for immunoassay techniques, such as ELISA, IP and WB.
See all GTF2E1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2C12
Antibody Isotype
IgG2a
Application
ELISA, IP, WB

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
GTF2E1
Introduction
GTF2E1 (general transcription factor IIE subunit 1), also known as transcription initiation factor IIE subunit alpha, is a protein that in humans is encoded by the GTF2E1 gene.
Entrez Gene ID
2960
UniProt ID
P29083
Alternative Names
FE; TF2E1; TFIIE-A
Function
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Biological Process
Transcription by RNA polymerase II Source: ARUK-UCL
Transcription initiation from RNA polymerase II promoter Source: ProtInc
Transcription open complex formation at RNA polymerase II promoter Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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