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Mouse Anti-GTF2E1 Recombinant Antibody (CBFYH-3486) (CBMAB-H4035-FY)

This product is mouse antibody that recognizes GTF2E1. The antibody CBFYH-3486 can be used for immunoassay techniques such as: WB, IHC, IF.
See all GTF2E1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Monkey, Mouse
Clone
CBFYH-3486
Antibody Isotype
IgG1
Application
WB, IHC, IF

Basic Information

Immunogen
Full length human recombinant protein of human GTF2F1 produced in HEK293T cell
Specificity
Human, Monkey, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, PH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% Sodium azide
Concentration
0.65 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
GTF2E1
Introduction
Analysis of gene expression patterns of placentas from a case-control study of preeclampsiausing Algorithm for Reconstruction of Accurate Cellular Networks (ARACNE) revealed GTF2E1,a component of TFIIE which modulates TFIIH.
Entrez Gene ID
Human2960
Mouse74197
Monkey713562
UniProt ID
HumanP29083
MouseQ9D0D5
MonkeyA0A2K5U0C5
Alternative Names
FE; TF2E1; TFIIE-A
Function
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Biological Process
Transcription by RNA polymerase II Source: ARUK-UCL
Transcription initiation from RNA polymerase II promoter Source: ProtInc
Transcription open complex formation at RNA polymerase II promoter Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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